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Computational & System Biology Branch

The Computational & Systems Biology Branch collaborates in the pre-clinical programs of the DCTD to utilize genomic and proteomic technology to identify molecular targets, resistance mechanisms and effective new drugs, drug combinations and biomarkers for guiding treatment. Members of the Computational & Systems Biology Branch conduct research on mechanisms of carcinogenesis and systems pharmacology. The branch develops bioinformatic systems to support genomic variant based clinical trials and to enhance the ability of biologists and pharmacologists to analyze and interpret genome-wide data. The branch also collaborates in the analysis of genomic data from the clinical trials program of the NCI. The Computational & Systems Biology Branch consists of doctoral level staff with diverse backgrounds such as computational biology, bioinformatics, computer science, biology, pharmacology, medicine and biomedical engineering.