Dr. Jared C. Foster
Mathematical Statistician, Biostatistics Branch
Research Interests
My primary interest is in the design, monitoring and analysis of oncology clinical trials, and I am particularly interested in phase II trials. In terms of statistical methodology, I am interested in problems relating to prediction, subgroup identification and variable selection, and much of my research has been in the area of personalized medicine.
Selected Peer Reviewed Papers:
Foster, JC, Taylor, JMG and Ruberg, SJ (2011), Subgroup identification from randomized clinical trial data, Statistics in Medicine, 30(24):2867-2880
Foster, JC, Taylor, JMG and Nan, B (2013), Variable selection in monotone single- index models via the adaptive LASSO, Statistics in Medicine, 32(22):3944-54
Foster JC, Freidlin B, Kunos CA, Korn EL: Single-Arm Phase II Trials of Combination Therapies: The CTEP Experience 2008-2017, Journal of the National Cancer Institute, djz193, https://doi.org/10.1093/jnci/djz193, 2019
Foster JC, Freidlin B, Korn EL, Smith MA, An Evaluation of the Contribution of Randomized Cancer Clinical Trials Evaluating Agents without Documented Single Agent Activity, ESMO Open 5(5), 2020
Tolaney SM, Garrett-Mayer E, White J, Blinder VS, Foster JC, Kordestani LA, Hwang ES, Bliss JM, Rakovitch E, Perlmutter J, Spears PA, Frank E, Tung NM, Elias AD, Cameron D, Denduluri N, Best AF, DiLeo A, Baizer L, Butler LP, Schwartz E, Winer EP and Korde LA, Updated standardized definitions for efficacy endpoints in adjuvant breast cancer clinical trials: STEEP Version 2.0 Journal of Clinical Oncology 2021 39:24, 2720-2731
Sharon E and Foster JC, Design of phase II oncology trials evaluating combinations of experimental agents, JNCI: Journal of the National Cancer Institute, 2023, djad052, https://doi.org/10.1093/jnci/djad052
Chen A, Sharon E, O'Sullivan G, Moore N, Foster J, Hu J, Van Tine B, Conley A, Read W, Riedel R, Burgess M, Glod J, Davis E, Naquash AR, Fino K, Miller B, Wilsker D, Begum A, Ferry-Galow K, Deshpande H, Schwartz G, Ladle B, Okuno S, Beck J, Chen J, Fogli L, Rosenberger CL, Parchment R, and Doroshow J, Atezolizumab for Advanced Alveolar Soft Part Sarcoma, N Engl J Med. 2023 Sep 7;389(10):911-921. doi: 10.1056/NEJMoa2303383. PMID: 37672694; PMCID: PMC10729808
Foster JC, Korn EL, Freidlin B, Moscow J, The potential to backfill in phase I trials: the National Cancer Institute's Cancer Therapy Evaluation Program experience, JNCI Cancer Spectrum, Volume 7, Issue 6, December 2023, pkad102, https://doi.org/10. 1093/jncics/pkad102
Office Address:
Room 5W638
9609 Medical Center Dr
Rockville, MD 20850
Contact Information:
Tel: (240) 276-7385
Fax: (240) 276-7888
Email:jared.foster@nih.gov