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Biometric Research Program (BRP)

Supplementary material to the publication in Clinical Epigenetics,

Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines

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Table S5


Significant strong trans- and cis-correlations of GMD expression with methylation of target gene regions in the pancancer dataset satisfying pFDR < 0.05 and |ρ| > 0.5



HEADER LEGEND:
- pFDR, FDR adjusted p-value
- |ρ|, the absolute value of the Spearman correlation coefficient
- Spearman ρ, Spearman correlation coefficient
- GMD, gene affecting DNA methylation or demethylation, expression of which was included in the correlation analysis
- Target gene, the gene for which methylation of a particular probe was analyzed in the correlation
- Target gene region, gene region whose methylation was analyzed in the correlation
- GMD chromosome, chromosome on which the GMD is located
- Target gene cytoband, chromosomal region where the target gene is located
- Sample size, number of cell lines with available data included in the correlation analysis

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Type of correlation GMD Target gene Target gene region Spearman pFDR GMD chromosome Target gene cytoband Sample size



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Type of correlation GMD Target gene Target gene region Spearman ρ
(|ρ | > 0.5)
pFDR GMD chromosome Target gene cytoband Sample size
Type of correlation GMD Target gene Target gene region Spearman ρ
(|ρ | > 0.5)
pFDR GMD chromosome Target gene cytoband Sample size
Type of correlation GMD Target gene Target gene region Spearman ρ
(|ρ | > 0.5)
pFDR GMD chromosome Target gene cytoband Sample size